当前位置:
首页
>
产品中心 >
Fluorescent_dyes >
Clickchemistrytools/6-azido-6-deoxy-N-acetyl-glucosamine triacylated (Ac3-6AzGlcNAc)/1258-100/100 mg
Clickchemistrytools/6-azido-6-deoxy-N-acetyl-glucosamine triacylated (Ac3-6AzGlcNAc)/1258-100/100 mg
市场价:
¥11900.00
美元价:
7140.00
产品分类:
荧光染料
公司分类:
Fluorescent_dyes
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
6-azido-6-deoxy-N-acetyl-glucosaminetriacylated(Ac36AzGlcNAc)isanazide-containing,specificmetabolicchemicalreporterforO-GlcNAcylatedproteins.Notably,6AzGlcNAccannotbebiosyntheticallytransformedintothecorrespondingUDPsugar-donorbythecanonicalsalvage-pathwaythatrequiresphosphorylationatthe6-hydroxyl.Invitroexperimentsshowedthat6AzGlcNAccanbypassthisroadblockthroughdirectphosphorylationofits1-hydroxylbytheenzymephosphoacetylglucosaminemutase(AGM1).Theazide-modifiedproteinisdetectedwitheitherfluorescentalkynesorbiotinalkyne.TheacetylgroupsincreasecellpermeABIlityandallowtheunnaturalsugarstoeasilypassthroughthecellmembrane.Carboxyesterasesremovetheacetylgroupsoncethemonosaccharideisinthecell.
Molecularweight | 372.33 |
Chemicalcomposition | C14H20N4O8 |
CAS | N/A |
Solubility | DMSO,DMF,DCM,THF,Chloroform |
Purity | >90% |
Appearance | Whitetogreyamorphoussolid |
Storageconditions | -20C |
Shippingconditions | Ambienttemperature |
品牌介绍
点击化学(Clickchemistry)蛋白质组学研究和新药研发的理想技术。美国一家小众里知名生物公司,国内通常称呼为 CCT,生产有浓缩介质,代谢标记试剂,生物素标记试剂,荧光染料以及交联剂。